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非致死性組織サンプリングを用いた両生類の水銀曝露推定

Caitlin T Rumrill1, Kelly L Smalling2, Colleen Emery3

  • 1U.S. Geological Survey, Forest and Rangeland Ecosystem Science Center, Corvallis Research Group, 3200 SW Jefferson Way, Corvallis, OR, 97331, USA. crumrill@gmail.com.

Ecotoxicology (London, England)
|February 18, 2026
PubMed
まとめ

No abstract available in PubMed .

キーワード:
汚染物質カエルモニタリングリスクサンショウウオ組織相関

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Toxicity Testing in Animals01:23

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Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...
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