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Updated: Feb 20, 2026

In Vitro Methods for Comparing Target Binding and CDC Induction Between Therapeutic Antibodies: Applications in Biosimilarity Analysis
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トシリズマブのバイオシミラーであるGNR-087の物理化学および生物学的特徴

Valentina D Gusarova1, Ivan V Lyagoskin1, Maksim B Degterev1

  • 1Pharmaceutical Analysis Department, JSC "GENERIUM", 14 Vladimirskaya street, Volginskiy, Petushinskiy district, Vladimir Region 601125, Russia.

Journal of pharmaceutical and biomedical analysis
|February 18, 2026
PubMed
まとめ

GNR-087はトシリズマブにバイオシミラーであり,構造,機能,および生物学的活性において高い分析的な比較性を示しています. わずかな差異は臨床的に無意味であり,リウマチ性関節炎の治療に使用することを支持しました.

キーワード:
アクテムラ (Actemra®) とはバイオシミラー バイオシミラーコンプラレート (Complarate) は,コンプラレート (Complarate) によるGNR-087 についてトシリズマブ (トシリズマブ) とは

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