RET融合陽性肺腺癌:パートナー特異的な臨床病理学的特徴,共変異プロファイル,および標的および免疫療法への影響

Zihan Sun1, Tianyi Liu2, Jiaxi Xu3

  • 1Department of Pathology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.

PubMed
まとめ

肺腺がん (LUAD) のRET融合は,異なるパートナーによって推進されます. 非KIF5B融合は,選択的RET阻害剤からより多くの利益を得ることができますが,免疫化学療法はすべてのRET融合タイプにわたって有効です.

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