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Updated: Feb 20, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
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高コレステロール負荷によって引き起こされる歯周線維芽細胞のピロプトーシスは,歯周炎を促します

Zhenxiang Wang1, Yueheng Li1, Hang Chen2

  • 1College of Stomatology, Chongqing Medical University, Chongqing, 401147, China; Chongqing Key Laboratory of Oral Diseases, Chongqing, 401147, China; Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing, 401147, China; Chongqing Municipal Health Commission Key Laboratory of Oral Biomedical Engineering, Chongqing, 401147, China.

International immunopharmacology
|February 18, 2026
PubMed
まとめ

高コレステロールは,歯茎組織の細胞死を引き起こし,歯周炎を悪化させます. NLRP3やキャセプシンB (CTSB) などの特定の経路をターゲットにすることで,歯周病のモデルにおける炎症と骨の損失を軽減することができます.

キーワード:
コレステロール コレステロール炎症性である.炎症 炎症 炎症 炎症 炎症歯周病 (periodontitis) とは,歯周病 (periodontitis) とは,歯周病 (periodontitis) とは,歯周病のことです.ピロプトーシス (Pyroptosis) とは

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