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Updated: Feb 20, 2026

Isolation and Flow Cytometric Analysis of Glioma-infiltrating Peripheral Blood Mononuclear Cells
12:52

Isolation and Flow Cytometric Analysis of Glioma-infiltrating Peripheral Blood Mononuclear Cells

Published on: November 28, 2015

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P4HA2は,EGFR/ERKシグナル伝達経路を活性化するためにHsp27と相互作用することによって,膠原腫細胞の増殖を促進します

Hongqing Cai1, Qi Liu2, Liyan Yang3

  • 1Department of Neurosurgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; State Key Laboratory of Molecular Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Cellular signalling
|February 18, 2026
PubMed
まとめ

プロリルヒドロキシラーゼP4HA2は,Hsp27相互作用を通じてEGFR/ERK経路を活性化することによって,膠原腫の進行を誘導する. P4HA2をターゲットにすることで,膠原腫の新たな治療戦略が提供され,患者の予後が改善されます.

キーワード:
EGFR/ERKのシグナリンググリオマ・グリオマ (glioma) とはHsp2727 についてP4HA2は,P4HA2と一致している.核拡散について

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