関連する実験動画

Updated: Feb 20, 2026

Recombinant α- β- and γ-Synucleins Stimulate Protein Phosphatase 2A Catalytic Subunit Activity in Cell Free Assays
09:36

Recombinant α- β- and γ-Synucleins Stimulate Protein Phosphatase 2A Catalytic Subunit Activity in Cell Free Assays

Published on: August 13, 2017

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タンパク質フォスファタゼ2A-B56α複合体は,神経芽細胞腫におけるN-Myc分解を調節する

Brian D Tran1, Irene Peris2, Ethan Wurman2

  • 1Department of Pharmacology, University of Michigan, Ann Arbor, Michigan, USA; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, USA.

The Journal of biological chemistry
|February 18, 2026
PubMed
まとめ

研究者らは,PP2Aを再活性化することで,神経芽細胞腫におけるN-Mycタンパク質を減少させ,MYCNの腫瘍性シグナリングをターゲットにすることで,高リスクの神経芽細胞腫に対する新しい治療戦略を提供することを発見しました.

キーワード:
N-Myccは,N-Myccという名前で使われています.がん がん がん がん がん がん がんがん治療の治療法である.分子粘着剤は分子粘着剤として使われています.タンパク質フォスファターゼ2 (PP2A)タンパク質セリン/スレオニンフォスファターゼ (PSP) ニューロブラストームタンパク質の安定性

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