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Updated: Feb 20, 2026

Molecular Analysis of Endothelial-mesenchymal Transition Induced by Transforming Growth Factor-β Signaling
07:49

Molecular Analysis of Endothelial-mesenchymal Transition Induced by Transforming Growth Factor-β Signaling

Published on: August 3, 2018

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TWIST1は,動脈硬化性プラークを安定させるために,内皮からメセンキマへの移行を促します

Blanca Tardajos Ayllon1, Mannekomba Diagbouga1, Ankita Das1

  • 1Centre for Microvascular Research, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

Nature communications
|February 18, 2026
PubMed
まとめ

内皮細胞のTwist1は,動脈硬化におけるプラークの安定性を促進し,内皮細胞からメゼンキマ細胞への移行に関する以前の見解に異議を唱える. この発見は,心血管疾患に対する新しい治療目標を提供します.

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