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Updated: Feb 20, 2026

Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions
08:31

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Published on: December 1, 2020

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MexBの基板結合ポケットを標的とした構造ベースの薬物設計

Praveena Nanjan1

  • 1Department of Biochemistry, School of Life Science, JSS Academy of Higher Education and Research, Longwood Campus, Mysuru Road, Ooty, India. praveenananjan29@gmail.com.

The protein journal
|February 18, 2026
PubMed
まとめ

多剤耐性Pseudomonas aeruginosa感染症は大きな脅威となっている. この研究では,抗生物質の耐性を克服し,抗生物質の有効性を回復するために,MexBトランスポーターを標的とした新種の流出ポンプ阻害剤 (EPI) を調査しています.

キーワード:
コンビネーション・セラピーは,エフフルスポンプ阻害剤 (EPI) とはメキシコのタンパク質MexBです.合理的な薬物デザインレジスタンス・ノドゥレーション・ディビジョン (RND) ファミリー構造生物学 構造生物学とは

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