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Updated: Feb 20, 2026

Utilizing Murine Inducible Telomerase Alleles in the Studies of Tissue Degeneration/Regeneration and Cancer
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産後発達中のKCC2の活性化は,CDKL5欠乏したマウスの長期的な赤字を軽減する

Muhammad Nauman Arshad1, Christopher Bope1, Noell Cho1

  • 1Department of Neuroscience, Tufts University School of Medicine, Boston, MA, USA.

Experimental & molecular medicine
|February 18, 2026
PubMed
まとめ

カリウム塩化物コトランスポーター (KCC2) 機能の強化は,サイクリン依存キナーゼ類似5 (CDKL5) 欠乏症障害 (CDD) の治療に役立ちます. 人生の初期にKCC2の活性化により,発作が減り,マウスモデルでの認知および行動的欠陥が改善されました.

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