プロバイオティクスとプレバイオティクスの国際科学協会 (ISAPP) のコンセンサス声明は,腸の健康の定義と範囲に関するものです
Maria L Marco1, Marla Cunningham2, Stephan C Bischoff3
1Department of Food Science and Technology, University of California, Davis, CA, USA. mmarco@ucdavis.edu.
Nature reviews. Gastroenterology & hepatology
|February 18, 2026
まとめ
腸の健康を定義することは,科学的および臨床的な理解にとって極めて重要です. 一致的な定義は,病気や生活の質に影響を与える症状のない正常な胃腸機能を強調しています.
科学分野:
- 胃腸内科と栄養科学 胃腸内科と栄養科学
- マイクロバイオーム研究
背景:
- "腸の健康"という用語は広く使われていますが,明確な科学的定義はありません.
- その応用は,食事,発酵食品,プロバイオティクス,プレバイオティクス,腸内微生物群に及ぶ.
研究 の 目的:
- 腸の健康に関する明確でコンセンサスに基づく定義を確立する.
- 腸の健康の生理学,表れ,測定に関する現在の知識をレビューする.
- 臨床実践と研究における腸の健康を評価するための枠組みを提案する.
主な方法:
- プロバイオティクスとプレバイオティクスの国際科学協会による専門家パネルの招集.
- 整体的な健康における胃腸の役割における腸の健康の概念を評価する.
- 腸の健康の機能的,主観的,外的な領域を評価するための臨床的に関連する指標のレビュー.
主要な成果:
- 腸の健康に関する提案された定義は",活発な胃腸疾患および生活の質に影響を与える腸関連の症状のない正常な胃腸機能の状態"である.
- この定義は,腸の健康に寄与する機能的,主観的,外的な要因を考慮します.
- これらの領域を評価するためのアクセシブルなメトリックの特定.
結論:
- 腸の健康に関する統一された定義は,一貫した研究と臨床応用のために不可欠です.
- 提案された定義は,腸の健康を理解し,測定するための枠組みを提供します.
- このコンセンサス声明は,介入と患者ケアに関連する腸の健康に関する包括的なアプローチを支持しています.
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