新しい精神活性物質の使用に関連した自己報告の副作用は,米国の20都市から成人のサンプルで報告されました
Nicole D Fitzgerald1, Joseph J Palamar2, Linda B Cottler3
1Department of Epidemiology, Columbia Mailman School of Public Health, New York, New York, USA.
Drug and alcohol review
|February 19, 2026
まとめ
新しい精神活性物質 (NPS) の副作用は一般的であり,使用者の4分の1以上が問題を報告しています. 多重物質の使用,特にオピオイドの使用は,これらの有害な効果のリスクを大幅に増加させます.
科学分野:
- 公衆衛生は公衆衛生である.
- 毒理学 毒理学 毒理学
- 薬物使用流行病学 薬物使用流行病学
背景:
- 新興の新精神活性物質 (NPS) は,死亡率を超えた悪影響に関する研究を必要とします.
- これらの影響を理解することは,効果的な予防と害の軽減戦略の開発に不可欠です.
研究 の 目的:
- 新しい精神活性物質 (NPS) の使用に関連した有害事象の有病率を決定する.
- これらの有害な影響を経験する危険因子,例えば多重物質の使用を特定する.
主な方法:
- 国立薬物早期警告システム・ラピッド・ストリート・リポート研究 (2022年1月~2023年11月) のデータを活用した.
- 米国20の都市で6039人の成人を対象に,会場・インターセプト・デザインを用いて調査を行った.
- 過去12ヶ月のNPSおよび他の薬物の使用と自己報告の副作用の評価.
主要な成果:
- NPSの使用を報告した個人の4分の1以上 (27.03%) が過去12ヶ月間に有害な影響を経験しました.
- オピオイドの使用を報告したNPS使用者は,有害事象の2倍以上の罹患率を示した (aPR 2.66).
- NPSの症状プロファイルは,一般的な薬物クラスと類似していました.
結論:
- 副作用は,自己報告したNPS使用者の間で一般的です.
- 多重物質の使用,特にオピオイドの使用は,NPSによる悪影響の可能性が高いと関連しています.
- NPSと他の薬物との併用に関連した特定の有害結果の詳細を明らかにするために,さらなる研究が必要です.
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