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Updated: Feb 20, 2026

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IL-21は,抗原活性化MAIT細胞の細胞毒性を選択的に増加させる

Laura E Wedlock1, Rajesh Lamichhane1, Meg C Webley1

  • 1Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand.

European journal of immunology
|February 19, 2026
PubMed
まとめ

インターリューキン-21 (IL-21) は,粘膜関連インヴァリアントT細胞 (MAIT) の細胞毒性を高めます. このサイトカインは,Granzyme BとPerforinのMAIT細胞発現を促進し,感染した細胞を排除する能力を向上させます.

キーワード:
IL‐21は,IL‐21で,IL‐21は,IL‐21で,IL‐21は,IL‐21で,IL‐21は,IL‐21で,IL‐21は,IL‐21で,TCRのアクティベーション同刺激による共刺激.サイト毒性 サイト毒性粘膜関連インヴァリアントT細胞

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