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Updated: Feb 20, 2026

Looking for Driver Pathways of Acquired Resistance to Targeted Therapy: Drug Resistant Subclone Generation and Sensitivity Restoring by Gene Knock-down
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Looking for Driver Pathways of Acquired Resistance to Targeted Therapy: Drug Resistant Subclone Generation and Sensitivity Restoring by Gene Knock-down

Published on: December 11, 2017

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がんにおけるDDR1の役割と標的治療戦略に関する研究の進展

Xiaoying Guan1,2, Yajie Zhang3, Xiaoli Guan4

  • 1Pathology Department, The Second Hospital and Clinical Medical School, Lanzhou University, Lanzhou, Gansu, China.

Neoplasma
|February 19, 2026
PubMed
まとめ

コラーゲン活性化キナーゼであるディスコイドリン領域受容体1 (DDR1) は,固体腫瘍の進行と化学抵抗を駆動する. DDR1を阻害剤または抗体で標的化することは,がん治療の有望な新しい戦略を提供します.

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