関連する実験動画

Updated: Feb 20, 2026

Methods to Inhibit Bacterial Pyomelanin Production and Determine the Corresponding Increase in Sensitivity to Oxidative Stress
11:00

Methods to Inhibit Bacterial Pyomelanin Production and Determine the Corresponding Increase in Sensitivity to Oxidative Stress

Published on: August 31, 2015

8.7K

ポリフェノル抗酸化剤は,ペロキシニート媒介によるDNA損傷を阻害するインビトロおよびE. コリ・コリー

Hsiao C Wang1, Nathan R Perron1, Fatema Tuz Zohara1

  • 1Department of Chemistry, Clemson University, Clemson, South Carolina 29634-0973, United States.

ACS pharmacology & translational science
|February 19, 2026
PubMed
まとめ

ポリフェノールは,病気に関連する分子であるペロキシニトリットによって引き起こされるDNA損傷を予防します. この研究は,ポリフェノール構造がそれらの抗酸化活性にどのように影響するかを明らかにし,病気の予防を理解するために不可欠です.

キーワード:
DNA損傷によるDNA損傷です.抗酸化物質 抗酸化物質 抗酸化物質細胞死亡 細胞死ペロキシニートリートポリフェノール (Polyphenols) とは,ポリフェノール (Polyphenols) とは,ポリフェノール (Polyphenols) とは,ポリフェノール (Polyphenols) とは,ポリフェノール (Polyphenols) とは,ポリフェノール (Polyphenols) とは,ポリフェノール (Polyphenols) とは,ポリフェノール (Polyphenols) とは,ポリフェノール (Polyphenols) とは,反応性窒素種;反応性酸素種に反応する.

さらに関連する動画

Author Spotlight: Quantitative Assessment of 8-oxo-dG in MCF-7 Cells Using ELISA05:13

Author Spotlight: Quantitative Assessment of 8-oxo-dG in MCF-7 Cells Using ELISA

Published on: May 24, 2024

1.9K
Quantification of three DNA Lesions by Mass Spectrometry and Assessment of Their Levels in Tissues of Mice Exposed to Ambient Fine Particulate Matter12:15

Quantification of three DNA Lesions by Mass Spectrometry and Assessment of Their Levels in Tissues of Mice Exposed to Ambient Fine Particulate Matter

Published on: May 29, 2019

9.2K

関連する概念動画

Oxidation of Phenols to Quinones01:17

Oxidation of Phenols to Quinones

In the presence of oxidizing agents, phenols are oxidized to quinones. Quinones can be easily reduced back to phenols using mild reducing agents. The electron-donating hydroxyl group enhances the reactivity of the aromatic ring, enabling oxidation of the ring even in the absence of an α hydrogen.
o-hydroxy phenols are oxidized to o-quinones and p-hydroxy phenols to p-quinones. Such redox reactions involve the transfer of two electrons and two protons. The reversible redox...
4.9K
Radical Autoxidation01:20

Radical Autoxidation

The oxidation of an organic compound in the presence of air or oxygen is called autoxidation. For example, cumene reacts with oxygen to form hydroperoxide. Autoxidation involves initiation, propagation, and termination steps. Many organic compounds are susceptible to autoxidation—especially ethers in the presence of oxygen, which form hydroperoxides. Even though this reaction is slow, old ether bottles contain small amounts of peroxide, which leads to laboratory explosions during ether...
3.3K
Nucleotide Excision Repair01:38

Nucleotide Excision Repair

DNA Distortion and Damage
Cells are regularly exposed to mutagens—factors in the environment that can damage DNA and generate mutations. UV radiation is one of the most common mutagens and is estimated to introduce a significant number of changes in DNA. These include bends or kinks in the structure, which can block DNA replication or transcription. If these errors are not fixed, the damage can cause mutations, which in turn can result in cancer or disease depending on which sequences are...
5.3K
Nucleotide Excision Repair01:08

Nucleotide Excision Repair

Overview
41.1K
Bioactivation and Tissue Toxicity01:25

Bioactivation and Tissue Toxicity

Bioactivation is a metabolic process that transforms less reactive substances into highly reactive metabolites, initiating tissue toxicity. This transformation can lead to various toxic effects, including carcinogenesis and teratogenesis. Reactive metabolites are classified into two main types: electrophiles and free radicals.Electrophiles are electron-deficient species and are produced primarily by the enzyme cytochrome P-450 during the metabolism of compounds containing carbon, nitrogen, or...
25
DNA Damage can Stall the Cell Cycle02:36

DNA Damage can Stall the Cell Cycle

In response to DNA damage, cells can pause the cell cycle to assess and repair the breaks. However, the cell must check the DNA at certain critical stages during the cell cycle. If the cell cycle pauses before DNA replication, the cells will contain twice the amount of DNA. On the other hand, if cells arrest after DNA replication but before mitosis, they will contain four times the normal amount of DNA. With a host of specialized proteins at their disposal,cells must use the right protein at...
10.2K