関連する実験動画
Updated: Feb 20, 2026

10:52
Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
Published on: March 30, 2018
11.7K
中枢神経系の原発性リンパ腫で,丸と前立腺が関与している: 症例報告
Javier A Rodríguez Morales1, Valeria Murguía Salgado1, Valdemar Barajas López2
1Department of Medicine and Nutrition, Universidad de Guanajuato, León, MEX.
Cureus
|February 19, 2026
まとめ
主要な中枢神経系分散型大B細胞リンパ腫 (DLBCL) は,免疫能力のある患者ではまれである. この症例は,早期に丸と前立腺に全身的に広がったことを示しており,徹底したステージ設定と迅速な治療を強調しています.
科学分野:
- 腫瘍学 腫瘍学
- 神経学 神経学とは
- 血液学 ヘマトロジ
背景:
- 拡散型大B細胞リンパ腫 (DLBCL) は,通常,結節疾患として現れる.
- 主要の中枢神経系 (CNS) DLBCLは,特に免疫力のある個体では珍しくありません.
- 早期の外節関わりが起こり,包括的な評価を必要とします.
研究 の 目的:
- 早期に全身に広がった原発CNSDLBCLの異常な症例を報告します.
- このような珍しいプレゼンテーションにおける診断と治療の課題を強調するためです.
- 徹底したステージングと治療プロトコルの重要性を強調する.
主な方法:
- 41歳の免疫力のある男性のケース報告です.
- 診断作業には,中枢神経系DLBCLの原発性神経イメージングと組織病理学が含まれていました.
- PET-CTを用いた全身的なステージングにより,外節関わりを特定しました.
- 治療は,高用量メトトレキサート,サイトラビン,リトゥキシマブを併用したマトリックス療法に従った.
主要な成果:
- 主要の中枢神経系のDLBCLの診断が確認されました.
- PET-CTでは,丸と前立腺領域の二次的な関与が明らかになりました.
- 患者は,中枢神経系の原発性リンパ腫のガイドラインに従って,高用量化学療法を受けた.
- このケースは,早期の全身的拡散の非典型的なパターンを示した.
結論:
- 主要の中枢神経系のDLBCLは,精巣および前立腺組織を含む稀有なエクストラノダルの関与を呈することがあります.
- PET-CTによる包括的なステージ測定は,系統的拡散の検出に不可欠です.
- 高用量メトトレキサートベースの化学療法の迅速な開始は,主要なCNS DLBCLにおける最適な結果のために不可欠です.
関連する概念動画
Primary Lymphoid Organs
16.1K
Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
16.1K
Secondary Lymphoid Organs
9.7K
Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
9.7K
Disorders of the Male Reproductive System
5.2K
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
5.2K
Lymphoid Cells and Tissues
3.4K
Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes.
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
3.4K

