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Updated: Feb 20, 2026

Preparation and Delivery of Protein Microcrystals in Lipidic Cubic Phase for Serial Femtosecond Crystallography
09:09

Preparation and Delivery of Protein Microcrystals in Lipidic Cubic Phase for Serial Femtosecond Crystallography

Published on: September 20, 2016

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GPCRリラクシン/インスリン類ファミリーペプチド受容体2の選択性小分子アゴニストを最適化するための構造活動関係研究

Kenneth J Wilson1, Maria Esteban-Lopez2, Courtney Myhr2

  • 1National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, Maryland 20850, United States.

Journal of medicinal chemistry
|February 19, 2026
PubMed
まとめ

研究者らは,リラクシン/インスリン類似ファミリーペプチド受容体2 (RXFP2) の最初の完全なアゴニストとして,新しい小分子,化合物68を特定しました. この強力な化合物は,さまざまな生理学的システムにおけるRXFP2の活性化を研究するための有望な結果を示しています.

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