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Updated: Feb 21, 2026

Quantifying Agonist Activity at G Protein-coupled Receptors
11:45

Quantifying Agonist Activity at G Protein-coupled Receptors

Published on: December 26, 2011

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インドール-3プロピオニック酸は,TAS2R3838の内生性アゴニストです

Yeeun Park1, Jin Yoo2, Na Young Kim3

  • 1Department of Food Science and Biotechnology, Ewha Womans University, Seoul 03760, Republic of Korea.

Journal of agricultural and food chemistry
|February 19, 2026
PubMed
まとめ

研究者らは,腸内代謝産物であるインドル3プロピオニン酸 (IPA) を,苦い味覚受容体38 (TAS2R38) の強力なアゴニストとして特定した. この発見は,代謝と免疫の健康をターゲットとした機能的な食品を開発するための新しい道を開きます.

キーワード:
アロマティックアミノ酸である.苦い味の受容体38 (TAS2R38) と呼ばれる.インドル-3-プロピオニック酸 (IPA)分子ドッキングシミュレーション

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