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Ophthalmologyにおけるインクリメンタル炭素フットプリント有効性比率

Sean T Berkowitz1, John C Buchan2, Aakriti Garg Shukla3

  • 1Cleveland Clinic Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio.

JAMA ophthalmology
|February 19, 2026
PubMed
まとめ

No abstract available in PubMed .

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Ophthalmic Drug Delivery Systems01:23

Ophthalmic Drug Delivery Systems

Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...
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