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Updated: Jun 4, 2026

Proteomics to Identify Proteins Interacting with P2X2 Ligand-Gated Cation Channels
16:36

Proteomics to Identify Proteins Interacting with P2X2 Ligand-Gated Cation Channels

Published on: May 18, 2009

P2RX7のコレステロール依存型構成変調と結合ホットスポット7:分子動力学シミュレーションと構造分析からの洞察

Mukesh Kumar1, Jayant Joshi1, Karuna Irungbam1

  • 1Division of Biochemistry, ICAR-Indian Veterinary Research Institute (ICAR-IVRI), Izatnagar 243122, India.

The journal of physical chemistry. B
|February 19, 2026
PubMed
まとめ

P2RX7受容体に結束するコレステロールは,その構造を安定させ,その機能を調節する. この研究は,主要なコレステロール相互作用部位を特定し,炎症,神経変性,がんに対する治療標的を提供している.

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