関連する実験動画

Updated: Jul 20, 2026

Single-cell Transcriptomic Analyses of Mouse Pancreatic Endocrine Cells
10:05

Single-cell Transcriptomic Analyses of Mouse Pancreatic Endocrine Cells

Published on: September 30, 2018

膵神経内分泌腫瘍のプロテオトランスクリプトーム分類と特性評価

Kevin C Yang, Steve E Kalloger, John J Aird

    Cell reports
    |February 19, 2026
    PubMed
    まとめ

    No abstract available in PubMed .

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    The pathophysiology of acute pancreatitis centers on injury to pancreatic acinar cells, which initiates a cascade of harmful intracellular events.This injury leads to premature activation of trypsinogen to trypsin in the pancreas. Trypsin then activates other digestive enzymes, such as chymotrypsin, elastase, and phospholipase A2, which begin breaking down pancreatic tissue. The resulting autodigestion causes local inflammation, tissue swelling, hemorrhage, and fat necrosis.Injured acinar cells...
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