アルコール飲料による全身殺虫剤に対するヒトの潜在的曝露:日本のサーキに関する最初の報告
Zanne Sandriati Putri1, Tadashi Kondoh2, Yoshinori Ikenaka3,4
1Department of Natural Environmental Studies, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Japan.
まとめ
系統的殺虫剤は,サケのサンプルの88%で発見され,ダイノテフランが最も一般的であった. 日本の基準では安全ですが,サケの汚染レベルは欧州連合 (EU) の飲料水限度を超えており,より厳しい規制が必要であることを示唆しています.
科学分野:
- 食品化学 食品化学について
- 環境科学 環境科学
- 毒理学 毒理学 毒理学
背景:
- 水性性全身殺虫剤は,処理された作物を通して食物連鎖に侵入することができます.
- 治療された作物から作られたアルコール飲料は,新興の食による暴露経路を示しています.
- 日本の米ワインであるサケは,以前は殺虫剤の汚染について研究されていなかった.
研究 の 目的:
- 特定の全身殺虫剤とその代謝産物のサケにおける発生を調査する.
- 検出されたレベルを規制上の限界値および確立された摂取値と比較してリスク評価を行う.
- これらの汚染物質を含むサケの消費に関連する潜在的なリスクを評価する.
主な方法:
- 日本の5つの県から52個のサケサンプルを分析した.
- 7つのネオニコチノイド,6つの代謝産物,クロラントラニリプロル,エチプロル,スルフォキサフロール,トリフルメゾピリムの検出.
- 液体染色体-タンデム質量スペクトロメトリ (LC-MS/MS) を用いた定量化.
主要な成果:
- システミックな殺虫剤は,サケのサンプルの88%で検出され,ディノテフランは最も頻繁に検出されました.
- サケの汚染レベルは,アジアの赤ワインに匹敵し,EUの赤ワインの汚染レベルを超えた.
- 日本の蛇口水の制限値を下回り,ADIにわずかに寄与しているものの,81%のサンプルは,EUの飲料水の基準値を超えた.
結論:
- サケは,全身殺虫剤に汚染され,潜在的リスクをもたらす可能性があります.
- 検出されたレベルは,特に国際規格に関する監視と規制の強化の必要性を示唆しています.
- 潜在的累積効果と相乗効果は,アルコール飲料における全身殺虫剤に関するさらなる調査とより厳格な制御を正当化します.
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