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Updated: Feb 21, 2026

Light-driven Enzymatic Decarboxylation
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エンジニアリングされたエネ-リデュークタゼの直接的可視光刺激によるエナチオセレクティブアルケンのアジド酸化

Jinhai Yu1,2, Qiaoyu Zhang3, Shiheng Zhang1

  • 1State Key Laboratory of Coordination Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Chemistry and Chemical Engineering, Frontier Interdisciplinary Science Research Center, Nanjing University, Nanjing 210023, China.

Journal of the American Chemical Society
|February 19, 2026
PubMed
まとめ

研究者らは,アルケンの非対称なアジド酸化のための新しい光酵素法を開発しました. この可視光駆動戦略は,エンジニアリングされたエネ・リデュークタゼ (ERED) を使用して,高収量とエナチオセレクティブ性を持つ有価なキラルベータ-オキシアジドを生成します.

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