アファンタジアを引き起こす病変は, fusiform 画像ノードに接続されています
Julian Kutsche1, Calvin Howard2, Alberto Castro Palacin3
1Center for Brain Circuit Therapeutics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Neurology with Experimental Neurology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; Berlin School of Mind and Brain, Department of Philosophy, Humboldt-Universität zu Berlin, Berlin, Germany.
まとめ
アファンタジアは,精神的に視覚化できないことであり,脳の機能と関連しています. 既得アファンタジアの原因となる病変は,視覚的精神的イメージにとって極めて重要な左側 fusiform 画像ノードに接続します.
科学分野:
- 神経科学は神経科学である.
- 認知心理学とは,認知心理学である.
- 神経画像は,神経イメージングによるものです.
背景:
- アファンタジア,視覚的精神的なイメージの先天的な欠如は,人口の3%までに影響します.
- アファンタジアと視覚的精神的イメージの背後にある正確な脳領域は,ほとんど不明のままです.
- 脳損傷による得られたアファンタジアは,視覚的精神的なイメージの神経解剖学へのユニークな窓を提供します.
研究 の 目的:
- 獲得したアファンタジアの神経解剖学的相関を特定するために.
- 視覚的精神的イメージにおける状イメージングノードの役割を調査する.
- 特定の脳領域と視覚的精神的イメージの能力との間の因果関係を確立する.
主な方法:
- 病変によるアファンタジアの症例を特定するための体系的な文献レビュー.
- 通常の脳アトラスに損傷をマッピングし,対照病変と比較する.
- 休息状態のfMRIデータを用いて,損傷部位と状画像ノード間の機能的接続性の分析.
- 敏感性と特異性に関するデータ駆動型全脳損傷接続性分析.
主要な成果:
- 脳損傷による獲得アファンタジアの12例が特定されました.
- 傷跡の位置は多様だが,左側 fusiform 画像ノードへの機能的な接続性を一貫して示した.
- 状画像ノードへの接続は,アファンタジアの敏感で特異的なマーカーでした.
結論:
- 既得アファンタジアは,様々な脳の領域の病変によるものですが,それらはすべて機能的に左側 fusiform 画像ノードと関連しています.
- この研究は,視覚的精神的イメージにおける状イメージングノードの重要な役割の因果的証拠を提供します.
- この発見は,視覚的精神的イメージとアファンタジアのニューラル基盤についての理解を深める.
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