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Updated: May 5, 2026

Generation of Immature, Mature and Tolerogenic Dendritic Cells with Differing Metabolic Phenotypes
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Generation of Immature, Mature and Tolerogenic Dendritic Cells with Differing Metabolic Phenotypes

Published on: June 22, 2016

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ホメオスタティックな成熟プログラムにより,ヒトのcDC2sは許容性の高い状態に変化します.

Mengmeng Lu1, Runpeng Han1, Hao Yang1

  • 1Department of Otolaryngology, Head and Neck Surgery, Medical Research Institute, Frontier Science Center for Immunology and Metabolism, Zhongnan Hospital of Wuhan University, State Key Laboratory of Virology and Biosafety, Wuhan University, Wuhan 430071, China; Department of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan 430071, China.

Immunity
|February 19, 2026
PubMed
まとめ

研究者らは, dendritic cells (DCs) がヒトの免疫耐性を維持するのに役立つ新しい方法を発見しました. 特定のタイプのDCは,従来型デンドリト細胞2型 (cDC2s) と呼ばれ,免疫過剰反応を防ぐために,調節性T細胞 (Tregs) を促進することができます.

キーワード:
dendritic 細胞とはホメオスタティック成熟免疫耐性 免疫耐性が高い規制T細胞は規制T細胞である胸膜のストロマルリンフォポイエチニンである.組織限定自己抗原は,組織限定自己抗原である.

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