関連する実験動画

Updated: Jul 2, 2026

Methods to Assess Beta Cell Death Mediated by Cytotoxic T Lymphocytes
12:12

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Published on: June 16, 2011

リピドドロップレット誘発のT細胞死は,自己免疫組織炎症を維持する

Jitendra Kumar1, Yoshinori Takashima1, Jose Morales1

  • 1Department of Medicine, Mayo Clinic Alix School of Medicine, Rochester, MN 55905, USA; Department of Immunology, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA; Department of Cardiovascular Medicine, Mayo Clinic Alix School of Medicine, Rochester, MN 55905, USA.

Cell metabolism
|February 19, 2026
PubMed
まとめ

リウマチ性関節炎のCD4+T細胞は,脂質が豊富な関節で死に,炎症物質を放出します. このピロプトーシス経路をターゲットにすることで,関節の炎症を抑制し,自己免疫疾患に対する新しい治療戦略を明らかにしました.

キーワード:
T細胞はT細胞である.自己免疫疾患は自己免疫疾患である.ガスダーミン D D炎症 炎症 炎症 炎症脂質のドロップレット ドロップレットS-アシレーションタンパク質のS-アシレーションです.ピロプトーシスである.

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