関連する実験動画

Updated: Jun 29, 2026

4D Imaging of Protein Aggregation in Live Cells
08:59

4D Imaging of Protein Aggregation in Live Cells

Published on: April 5, 2013

集積傾向のタンパク質の微分インクルージョン形成は,神経細胞系タンパク質のプロテオスタシス能力の違いを明らかにする

Shannon McMahon1, Dezerae Cox2, Flora Cheng3

  • 1Molecular Horizons and School of Science, University of Wollongong, Wollongong, Australia.

Biochimica et biophysica acta. Molecular cell research
|February 19, 2026
PubMed
まとめ

モーターニューロンのような細胞は,プロテオスタシス能力が低下し,神経芽細胞と比較してより多くのタンパク質の集積につながります. これは,神経変性疾患の研究において極めて重要な,タンパク質の誤折り合いを管理する細胞タイプの違いを強調しています.

キーワード:
アグリゲーション・インデックス (Aggregation Index) とは含めること 含めること 含めること神経変性疾患 神経変性疾患プロテインアグレゲーション (Protein Aggregation) についてプロテオスタシスの能力

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