関連する実験動画

Updated: Jul 6, 2026

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
10:33

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

Published on: October 26, 2015

PROTACの薬剤発見のためのコンピューティング方法の進歩

Massyel S Martinez-Cortés1, Carlos A Velázquez-Martínez2, José L Medina-Franco1

  • 1DIFACQUIM Research Group, Department of Pharmacy, School of Chemistry, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.

Drug discovery today
|February 19, 2026
PubMed
まとめ

タンパク質分解を標的とするキメラ (PROTACs) は,標的タンパク質を分解することによって,新しい薬剤発見アプローチを提供します. このレビューでは,PROTACの設計,最適化,および臨床翻訳を支援するコンピューティングツールを詳細に説明します.

キーワード:
人工知能 (AI) は,人工知能 (AI) を利用する.化学情報学 化学情報学コンピュータによる分子設計.機械学習 (Machine Learning) とは,機械学習 (Machine Learning) とは,機械学習 (Machine Learning) と呼ばれるものです.分子ダイナミクス 分子ダイナミクス

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