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Gastrointestinal Motility Disorders01:20

Gastrointestinal Motility Disorders

Gastrointestinal or GI motility disorders are characterized by irregular gastrointestinal tract movements, disrupting food transit from the mouth to the anus. They are caused by damage or dysfunction in gut muscles or nerves. These disorders can cause symptoms such as severe constipation, diarrhea, abdominal pain, and swallowing difficulties. Disorders can affect any segment of the GI tract and range widely in severity, from common conditions like GERD to life-threatening conditions like...
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Other Disorders of Digestive System01:30

Other Disorders of Digestive System

The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease I: Introduction01:26

Inflammatory Bowel Disease I: Introduction

Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...
Irritable Bowel Syndrome01:23

Irritable Bowel Syndrome

DefinitionIrritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterized by recurrent combinations of abdominal pain, bloating, diarrhea, or constipation.Pathophysiology of irritable bowel syndromeIts pathophysiology is multifactorial, involving disturbances in motility, sensory processing, microbial balance, barrier integrity, and gut–brain communication. These mechanisms interact to produce symptoms that vary across IBS subtypes.Altered Motility PatternsDisordered...

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Using Multi-fluorinated Bile Acids and In Vivo Magnetic Resonance Imaging to Measure Bile Acid Transport
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Using Multi-fluorinated Bile Acids and In Vivo Magnetic Resonance Imaging to Measure Bile Acid Transport

Published on: November 27, 2016

腸内障害 (BOWEL DISORDER) について

Maura Corsetti1, Andrea Shin2, Brian E Lacy3

  • 1NIHR Nottingham Biomedical Research Centre (BRC), Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham Digestive Diseases Centre, School of Medicine, University of Nottingham, Nottingham Digestive Diseases Biomedical Research Centre, Nottingham, UK.

Gastroenterology
|February 19, 2026
PubMed
まとめ
この要約は機械生成です。

ローマV分類は,腸疾患 (BDs) の診断を更新し,その原因と治療法に関する新しい洞察を提供します. この改訂された枠組みは,これらの一般的な疾患に対する患者ケアと研究を改善することを目的としています.

キーワード:
腹の痛み 腹の痛み 腹の痛み膨らむ 膨らむ 膨らむ便秘 便秘 便秘腹 腹 腹 腹

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科学分野:

  • 胃腸内科 胃腸内科
  • クリニカル・メディシン 臨床医学
  • エピデミオロジー エピデミオロジー

背景:

  • 以前は機能性腸疾患であった腸内疾患 (BD) は,世界的に蔓延しており,生活の質に影響を及ぼし,大きな経済的コストを負う.
  • ローマIV基準 (2016年) 以降の最近の研究は,BDの流行病学,病因学,病理生理学,診断,治療に関する理解を深めた.

研究 の 目的:

  • 腸疾患の更新されたローマV分類を提示する.
  • 最近の科学の進歩に基づいて,BDの診断の枠組みを改訂する.

主な方法:

  • BDsに関連する基礎科学と臨床科学における現在の研究のレビューと合成.
  • 改訂された診断基準の開発は,ローマV BD委員会によって行われました.

主要な成果:

  • ローマV分類では,6つの異なるBDカテゴリーを定義しています: 刺激性腸症候群,慢性便秘,機能性下痢,機能性腹部膨胀,未分類BD,オピオイド誘発性便秘.
  • 各カテゴリーには,更新された定義,疫学,変更の根拠,臨床評価,病理生理学,治療戦略が含まれています.

結論:

  • ローマV分類は,腸疾患の診断と管理を強化するための更新された枠組みを提供します.
  • この改訂は,臨床医と研究者が患者のケアとこれらの一般的な状態の科学的理解を進めるのを助けると期待されています.