トロンボエラストグラフィーで監視された25ヶ月の子供のリバロキサバンによる事故性中毒:症例報告

Keita Nakanishi¹, Shota Yamasaki², Yuna Watanabe¹

¹Department of Pediatrics, Akashi Medical Hospital, Hyogo, Japan.

The Kobe journal of medical sciences

|February 19, 2026

まとめ

子供が不意にリバロキサバンの大量を摂取した. トロンボエラストグラフィー (TEG® 6s) によるモニタリングは,凝固機能が20時間以内に正常化することを示し,小児症例での有用性を示した.

科学分野:

小児救急医療について
薬理学薬理学とは
クリニカル・コアグレーション

背景:

リバロキサバンは直接作用するXA因子阻害剤です.
トロンボエラストグラフィー (TEG® 6s) は,凝固を評価し,しばしば外科手術の際に使用されます.
小児におけるリバロキサバン過剰投与におけるTEG® 6sに関するデータは限られている.

研究の目的:

小児におけるリバロキサバン摂取の症例を報告するためです.
TEG® 6sの過剰投与後の凝固のモニタリングにおける有用性を評価する.
子どもの安全性と回復プロフィールを評価する.

主な方法:

25ヶ月の少女が不意にリバロキサバンを摂取したケース報告.
TEG® 6s.を使用した継続的な凝固モニタリング.
出血の発生に関する臨床観察.

主要な成果:

提示時に明らかな出血はありません.
TEG® 6s値は,摂取後約20時間後に正常化しました.
患者は合併症や出血なしに退院しました.

結論:

TEG® 6sは,小児の過剰投与におけるリバロキサバンの効果を監視するための貴重なツールである可能性があります.
子供の間で偶然の大量のリバロキサバンを摂取した場合には,注意深く観察することで管理することができます.
凝固パラメータの正常化は,抗凝固剤効果からの回復を示唆しています.

キーワード:

ファクターXA阻害剤は家庭での事故について新しい経口抗凝固剤過剰摂取は過剰摂取です.TEG® 6sは,TEG® 6sと一致しています.

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