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Updated: May 1, 2026

Ferric Chloride-induced Murine Thrombosis Models
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Published on: September 5, 2016

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コノトキシン由来ペプチドは,血液静止に影響を与えることなく,PAR-1媒介性血栓症と中性粒子の細胞外トラップ形成を選択的に抑制する

Aili Wang1, Tianyu Wang2, Haidong Chen2

  • 1Center for Evolution and Conservation Biology, Southern Marine Science and Engineering Guangdong Laboratory Zhanjiang, Zhanjiang, China.

Thrombosis and haemostasis
|February 19, 2026
PubMed
まとめ

新しいペプチド,Cb-26は,コナス種から派生した. 毒は,血栓形成を防ぐためにプロテアゼ活性化受容体-1 (PAR-1) を選択的に抑制する. この有望な抗血栓剤は,出血リスクを高めることなく,脳卒中モデルでの有効性を示しています.

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