BRCA1BRCA2,:IMPACT5

Elizabeth K Bancroft1, Elizabeth C Page2, Jana McHugh2

  • 1Oncogenetics Team, Genetics and Epidemiology, The Institute of Cancer Research, London, UK; Cancer Genetics Unit and Academic Urology Unit, The Royal Marsden NHS Foundation Trust, London, UK.

European urology
|February 19, 2026
PubMed
まとめ

BRCA1/BRCA2の病原性生殖系変種 (PGVs) を有する男性におけるPSAを用いた前立腺がん (PC) スクリーニングでは,BRCA2のキャリアにおいて臨床的に有意なPCの高い割合が確認されました. 関連する腫瘍の早期発見は,BRCA1キャリアでも認められた.

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