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Updated: Jun 15, 2026

High Throughput, Real-time, Dual-readout Testing of Intracellular Antimicrobial Activity and Eukaryotic Cell Cytotoxicity
09:09

High Throughput, Real-time, Dual-readout Testing of Intracellular Antimicrobial Activity and Eukaryotic Cell Cytotoxicity

Published on: November 16, 2016

アジトロマイシン即時放出錠剤の承認後の変化のバイオ医薬品評価 予測型インビトロ溶解とモデル情報型アプローチを用いて

Mauricio A García1, Pablo M González2

  • 1Departamento de Farmacia, Escuela de Química y Farmacia, Facultad de Química y de Farmacia, Pontificia Universidad Católica de Chile, 7820436, Santiago, Chile. magarci3@uc.cl.

Pharmaceutical research
|February 19, 2026
PubMed
まとめ

この研究では,予測的な溶解とモデリングを使用して,アジトロマイシン錠剤の承認後の変化を評価しました. 結果は,吸収が透過性によって制限されていることを示しており,配方評価のモデルベースのアプローチを支持しています.

キーワード:
アジトロマイシン IR タブレットバイオ医薬品の評価についてモデル情報に基づいたモデルです.承認後の変更について予測された in vitro 溶解を予測した.バーチャル・バイオ・エクイワレンス

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