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Updated: May 12, 2026

Two Methods of Heterokaryon Formation to Discover HCV Restriction Factors
16:49

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HBV pgRNA ゲノムの構造的組織は,カプシド収束における相分離によって引き起こされる

Yunqiang Bian1,2, Hai Pan1, Jiaqi Mao2,3

  • 1Wenzhou Key Laboratory of Biophysics, Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou, Zhejiang, PR China.

Nature communications
|February 19, 2026
PubMed
まとめ

B型肝炎ウイルス (HBV) のRNAは,液体-液体相分離 (LLPS) を使用して,そのゲノムをカプシド内で組織化し,空洞の殻を形成します. この構造はウイルスの複製を促進し,新しい抗ウイルス標的を提供します.

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