関連する実験動画

Updated: Jun 18, 2026

RiboTag Immunoprecipitation in the Germ Cells of the Male Mouse
10:00

RiboTag Immunoprecipitation in the Germ Cells of the Male Mouse

Published on: March 4, 2020

PAN2は,mRNAポリ(A) テイル・ホメオスタシスを維持し,マウスの精子生成中にトランスレーションを調節する

Xuan Wu1, Yu-Ke Wu1, Meng-Yan Jia1

  • 1Life Sciences Institute, Zhejiang Key Laboratory of Precise Protection and Promotion of Fertility, Assisted Reproduction Unit, Department of Obstetrics and Gynecology, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou, China.

Nature communications
|February 19, 2026
PubMed
まとめ

PAN2酵素は,その欠乏が精子発達の停止を引き起こすため,男性の生育能力にとって極めて重要です. PAN2の喪失はmRNAのポリ (A) 尾の調節を妨害し,トランスレーション効率と精子細胞の分化に影響を与えます.

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