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Updated: May 11, 2026

Manufacturing Chimeric Antigen Receptor (CAR) T Cells for Adoptive Immunotherapy
06:51

Manufacturing Chimeric Antigen Receptor (CAR) T Cells for Adoptive Immunotherapy

Published on: December 17, 2019

治療不耐性自己免疫結合組織疾患に対する二固有のT細胞エンゲージャー

Christina Düsing1,2,3, Andrea-Hermina Györfi1,2,3, Ayla Nadja Stütz1,2

  • 1Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich-Heine University, Düsseldorf, Germany.

Nature medicine
|February 19, 2026
PubMed
まとめ

ブリナトゥモマブとテクリスタマブは,重度の抗合成酵素症候群 (ASyS) と全身性硬化症 (SSc) の救済療法として有望であることが示されています. これらのT細胞エンゲージャー (TCE) は,治療抵抗性の患者で症状を改善し,自己抗体を減少させた.

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