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Updated: Feb 21, 2026

Examining BCL-2 Family Function with Large Unilamellar Vesicles
08:35

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Published on: October 5, 2012

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BCL-2はどんな作用をするのか? 新しい分子洞察から臨床的影響まで

Carlo M Croce1, Stephen W G Tait2,3, Ana J Garcia-Sáez4,5

  • 1Department of Cancer Biology and Genetics and Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA. Carlo.Croce@osumc.edu.

Cell death and differentiation
|February 19, 2026
PubMed
まとめ

数十年にわたるBCL-2ファミリータンパク質の研究は,BCL-2阻害剤の開発につながり,アポトーシスを標的としてがん治療に革命をもたらしました. 耐性メカニズムを理解し,新しい治療法を探求することは,がん治療の将来の進歩の鍵です.

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