関連する実験動画

Updated: Feb 21, 2026

High-throughput Screening for Broad-spectrum Chemical Inhibitors of RNA Viruses
11:34

High-throughput Screening for Broad-spectrum Chemical Inhibitors of RNA Viruses

Published on: May 5, 2014

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抗ウイルスプロファイリングとカルビサイクリックヌクレオシドアナログの細胞活性化

Stephan Scheeff1, Joan Marie Javillo Baguio2,3, Benny Zhibin Liang4,5

  • 1School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong.

Journal of medicinal chemistry
|February 20, 2026
PubMed
まとめ

研究者らは,カーボサイクリック・スキャフォルドを使った新しい核酸類同類剤を開発し,インフルエンザなどのウイルスに対して広範な抗ウイルス活性を示した. これらの化合物は,ウイルスポリメラーゼを破壊し,ヒトDNA/RNAポリメラーゼの毒性を回避し,有望な新しい治療アプローチを提供します.

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