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Updated: Jun 9, 2026

Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells
10:21

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Published on: February 21, 2018

ENPP3は,cGAMPの水解とSTING-IFN抑制によってccRCCの進行を促します

Jiaxing Ma1, Yayun Wu2, Guangzheng Lin1

  • 1Department of Urology, Second Affiliated Hospital of Anhui Medical University, Hefei, China.

Cancer biology & therapy
|February 20, 2026
PubMed
まとめ

エクトヌクレオチド・パイロフォスファタゼ/フォスフォディエステラーゼ3 (ENPP3) は,クリア細胞腎臓細胞癌 (ccRCC) の低酸素誘発酵素である. ターゲティングENPP3は,抗腫瘍免疫を再活性化し,ccRCCに対する新しい治療戦略を提供します.

キーワード:
ENPP3 についてcGAMP-STING ストリングccRCCは,CCRCCと一致している.腫瘍に関連したマクロファージI型インターフェロンである.

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