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Updated: May 13, 2026

Development of a Backbone Cyclic Peptide Library as Potential Antiparasitic Therapeutics Using Microwave Irradiation
08:48

Development of a Backbone Cyclic Peptide Library as Potential Antiparasitic Therapeutics Using Microwave Irradiation

Published on: January 27, 2016

イソプセドプロリンが,後期的なペプチド骨幹の改変のための多用途なツールである.

Karen D Milewska1,2, Brett D Schwartz1,2, Jemimah R Canning1,2

  • 1Research School of Chemistry, Australian National University Canberra ACT 2601 Australia lara.malins@anu.edu.au.

Chemical science
|February 20, 2026
PubMed
まとめ

この研究は,ペプチド設計のための新しいイソプセドプロリン,チアゾリジン-2-カルボキシル酸 (2-Thz),セレナゾリジン-2-カルボキシル酸 (2-Sez) を導入しています. これらの残基は,還元環の開きを通じて,後期段階のペプチド骨幹の改変を可能にし,多様なペプチド誘導体を生み出します.

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Covalently Linked Protein Regulators02:04

Covalently Linked Protein Regulators

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These groups modify specific amino acids in a protein.
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Protein Modifications in the RER

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