リンフォトキシンベータ受容体のプレオトロプ的および多細胞的な役割は,固体腫瘍の免疫と治療的標的化におけるものです

Anshu1, Nair Shantikumar V1, Roy Sreeja1

  • 1Amrita Research Center Delhi NCR, Amrita Vishwa Vidyapeetham Faridabad, Faridabad, Haryana, India.

Frontiers in immunology
|February 20, 2026
PubMed
まとめ

リンパ毒素ベータ受容体 (LTβR) は,がん免疫における二重の役割を示しています. 戦略的なLTβR活性化により,腫瘍のマイクロ環境を再プログラムすることができ,PDAC,GBM,TNBCなどの固体腫瘍に対する免疫療法の有効性を高めることができます.

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