関連する実験動画

Updated: Feb 21, 2026

A High-content In Vitro Pancreatic Islet β-cell Replication Discovery Platform
09:35

A High-content In Vitro Pancreatic Islet β-cell Replication Discovery Platform

Published on: July 16, 2016

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β細胞の機能不全と置換の試験的な治療法

Domenico Accili1, Wen Du2, Takumi Kitamoto3,4

  • 1Department of Medicine, Vagelos College of Physicians and Surgeons of Columbia University, New York, NY 10032 USA.

Diabetology international
|February 20, 2026
PubMed
まとめ

研究者らは,2型糖尿病治療のターゲットとしてアルデヒド脱水素酵素亜型1A3 (ALDH1A3) を特定した. 小分子FoxO1阻害剤は,腸内細胞をインスリン生成細胞に変換することで,タイプ1糖尿病の治療に有望であることが示されています.

キーワード:
脱差分化とは糖尿病 糖尿病 糖尿病薬物開発 薬物開発腸内分泌細胞細胞は,腸内分泌細胞である.タイプ1 タイプ1タイプ2 タイプ2

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