関連する実験動画

Updated: Feb 21, 2026

Conversion of Human Induced Pluripotent Stem Cells iPSCs into Functional Spinal and Cranial Motor Neurons Using PiggyBac Vectors
07:33

Conversion of Human Induced Pluripotent Stem Cells iPSCs into Functional Spinal and Cranial Motor Neurons Using PiggyBac Vectors

Published on: May 1, 2019

12.2K

誘発性多能幹細胞ベースの化学遺伝的アプローチで,脊髄筋縮を研究する

Richard M Giadone1,2,3, Kristina M Holton1,2,3,4, Xiaoyu Hu1,2

  • 1Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, United States.

Frontiers in neuroscience
|February 20, 2026
PubMed
まとめ

研究者は,脊髄筋縮 (SMA) 研究のための新しいツールであるCMAPneuroを開発しました. このプラットフォームは,SMAニューロンの遺伝子発現を分析し,この遺伝疾患および中枢神経系に影響を与える他の疾患に対する潜在的な治療法を特定します.

キーワード:
L10001000 L10001000 L10001000 L10001000 L10001000 L10001000 L10001000 L10001000 L10001000 L10001000 L10001000 L10001000 L10001000 L10001000化学遺伝子スクリーニング 化学遺伝子スクリーニングコネクティビティマップの地図iPSCsは,iPSCsという名前で,iPSCsは,iPSCsという名前で,iPSCsは,iPSCsという名前で,iPSCsは,iPSCsという名前で,iPSCsは,iPSCsという名前で呼ばれています.脊髄筋縮 筋縮 脊髄筋縮 筋縮

さらに関連する動画

Analyzing Mitochondrial Transport and Morphology in Human Induced Pluripotent Stem Cell-Derived Neurons in Hereditary Spastic Paraplegia07:32

Analyzing Mitochondrial Transport and Morphology in Human Induced Pluripotent Stem Cell-Derived Neurons in Hereditary Spastic Paraplegia

Published on: February 9, 2020

8.3K
Generation of Induced Pluripotent Stem Cells from Muscular Dystrophy Patients: Efficient Integration-free Reprogramming of Urine Derived Cells09:11

Generation of Induced Pluripotent Stem Cells from Muscular Dystrophy Patients: Efficient Integration-free Reprogramming of Urine Derived Cells

Published on: January 28, 2015

11.7K

関連する概念動画

Induced Pluripotent Stem Cells01:06

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different cell types. Ordinarily, cells that have differentiated into a specific cell type are terminally differentiated; however, scientists have found a way to reprogram these mature cells so that they dedifferentiate and return to an unspecialized, proliferative state. These cells are pluripotent like embryonic stem cells—able to produce all cell types—and are called induced pluripotent stem cells (iPSCs).
Somatic...
5.7K
Induced Pluripotent Stem Cells01:13

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore...
28.2K
Satellite Stem Cells and Muscular Dystrophy01:21

Satellite Stem Cells and Muscular Dystrophy

Satellite stem cells or myosatellite cells are quiescent stem cells that Alexander Mauro first identified in 1961. These cells are located between the sarcolemma, the plasma membrane of muscle fibers, and the basal lamina, the connective tissue sheath covering it. These mononucleated cells are activated in response to muscle injury, can transform into myoblasts, and may form or repair muscle fibers. Myosatellite cells can provide additional myonuclei for muscle regeneration or return to a...
2.4K
EPS and iPS Cells in Disease Research01:21

EPS and iPS Cells in Disease Research

Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...
3.5K