PDC経由でM2マクロファージの極化を標的的に抑制することは,PPARα経路経由で慢性炎を弱める

Xin Kong1,2, Xufeng Tao1, Hong Xiang3

  • 1Department of Pharmacy, First Affiliated Hospital of Dalian Medical University, Dalian 116011, China.

iScience
|February 20, 2026
PubMed
まとめ

この研究では,M2マクロファージを阻害することによって,慢性炎 (CP) を治療するための標的ペプチド-薬物結合剤を開発しました. コンジュガートは,より低毒性で効果的に臓損傷と炎症を軽減し,新しい治療戦略を提供しました.

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