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Updated: May 10, 2026

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
11:15

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors

Published on: September 20, 2016

多様な固体腫瘍における包括的なゲノムプロファイリング: FoundationOne®CDxテストによるインドからの現実世界の経験

Pramod K Julka1, Deepika Arya1, Sanjay Gupta2

  • 1Medical Oncology, Max Super Speciality Hospital, Saket, Delhi, IND.

Cureus
|February 20, 2026
PubMed
まとめ

FoundationOne®CDx (F1CDx) の包括的なゲノムプロファイリングは,様々な固体腫瘍を有するインド人の患者で,さまざまな実行可能なゲノム変異を特定しました. このアプローチは,精密腫瘍学を進歩させ,現実世界でのターゲティングセラピーの選択肢を拡大するための大きな可能性を示しています.

キーワード:
foundationone®cdxxが提供されている.ゲノムプロファイリングはゲノムプロファイリングです.ngsテスト テスト精度の腫瘍学ソマティック突然変異 (somatic mutation) とは,体内での突然変異である.

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Cancers Originate from Somatic Mutations in a Single Cell02:21

Cancers Originate from Somatic Mutations in a Single Cell

Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...