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Updated: May 5, 2026

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
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化学療法未経験の前立腺がんにおけるPSMA標的治療前のゲノム解析

Mariam Amghar1, Mareike Roscher2, Tobias Rausch3

  • 1Junior Research Group Translational Radiotheranostics, German Cancer Research Center (DKFZ), Heidelberg, Germany.

Frontiers in oncology
|February 20, 2026
PubMed
まとめ

化学療法未経験の転移性カストレーション耐性前立腺がん (mCRPC) の患者で,PSMA-RPTを併用した治療を受けた患者は,特定のゲノム変化を示しています. ベースラインの循環腫瘍DNA (ctDNA) 分析は,これらのまれなケースでは,8pの損失と8qの増加のような,繰り返し発生する染色体不均衡を明らかにします.

キーワード:
PSMAは,PSMAは,PSMAは,PSMAは,PSMAは,PSMAはcfDNA cfDNAとは化学療法-ナイヴでした.コピーナンバーの交代,コピー番号の交代.mCRPCは,mCRPCとして使用されています.放射線薬剤療法による放射線薬剤療法タンドムアクティニウム-ルテチウム療法

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