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Updated: Feb 22, 2026

A Real-time Electrical Impedance Based Technique to Measure Invasion of Endothelial Cell Monolayer by Cancer Cells
08:51

A Real-time Electrical Impedance Based Technique to Measure Invasion of Endothelial Cell Monolayer by Cancer Cells

Published on: April 1, 2011

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癌の進行におけるターゲットとしてのポドカリシン-エズリン相互作用に関する構造的およびダイナミックな洞察

Mila Milutinovic1, Stuart Lutimba1, Mohammed A Mansour1,2

  • 1Cancer, Infection and Therapeutics Laboratory, School of Allied Health and Life Sciences, College of Health and Life Sciences, London South Bank University, 103 Borough Road, London SE1 0AA, UK.

Journal of xenobiotics
|February 20, 2026
PubMed
まとめ

研究者らは,がんタンパク質ポドカリキシン (PODXL) がエズリンと相互作用する方法を明らかにし,がんの広がりを促進する可能性がある変異を特定しました. NSC305787という化合物が,この変異したPODXL複合体を選択的に標的にすることが判明しました.

キーワード:
エズリン・エズリン EzrinPODXL PODXL についてR495W変異による変異生物物理モデリング癌の転移による転移です.

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