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Updated: Feb 22, 2026

Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway
07:15

Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway

Published on: August 23, 2024

978

メトホルミンはAMPKを活性化させ,カドミウム神経毒性におけるミトコンドリアのROS誘発性死滅を抑制する

Xiaoling Chen1,2, Haifeng Zhang2, Wenjie Zhang1

  • 1Department of Blood Transfusion, the First Affiliated Hospital of Wannan Medical College, Wuhu, China.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
|February 20, 2026
PubMed
まとめ

カドミウム曝露は,死滅を引き起こすことで神経変性を引き起こす. メトホルミンは,AMPKを活性化させ,ミトコンドリアのROSを減少させ,この細胞死経路を阻害することによって,ニューロンを保護します.

キーワード:
AMPKK は AMPKK と呼ばれています.カドミウム カドミウムメトフォーミン (Metformin) とはmtROSROS についてネクロプトーシス (necroptosis) とは

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