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Updated: Feb 22, 2026

An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP
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An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP

Published on: January 27, 2010

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CYP2D6によるオピオイド管理と術後の疼痛管理:ランダム化臨床試験

Larisa H Cavallari1,2, Rachel A Myers3, Hrishikesh Chakraborty4

  • 1Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville.

JAMA network open
|February 20, 2026
PubMed
まとめ

CYP2D6の代謝に関する遺伝検査は,オピオイドの処方を誘導したが,代謝が遅いまたは中間の代謝者における術後の痛みのコントロールを改善することはなかった. この研究は,CYP2D6誘導療法が,現在のマルチモデルのアプローチで外科痛みの管理に有益でないことを示唆しています.

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