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Updated: Feb 22, 2026

Biochemical Reconstitution of Steroid Receptor•Hsp90 Protein Complexes and Reactivation of Ligand Binding
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ステロイド受容体共同活性化剤 - 基礎研究から翻訳的な機会まで

Yosef Gilad1, Sang Jun Han1,2, David M Lonard1,2

  • 1Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, United States.

Endocrine reviews
|February 20, 2026
PubMed
まとめ

核受容体 (NRs) は同調子によって調節され,独立したものではない. ステロイド受容体共同活性化剤 (Steroid Receptor Coactivator,SRC) 家族は,NR機能の重要な調節体であり,生理学と腫瘍学における重要な治療標的である.

キーワード:
免疫療法による免疫療法です.核受容体コーレグレーターのコーレグレーターステロイド受容体共同活性化剤 (SRC)治療に対する抵抗性があります.

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