ホルモン置換療法と髪: 更年期女性を治療するトリコロジストのためのレビュー
まとめ
ホルモン置換療法 (HRT) は髪の毛に影響しますが,その効果は複雑で,完全に理解されていません. このレビューでは,髪の生物学におけるホルモンの役割と,現在のHRTの証拠を調査します.
科学分野:
- エンドクリノロジー エンドクリノロジー
- 皮膚科 皮膚科について
- 髪の生物学 髪の生物学について
背景:
- ホルモンは,毛の機能と頭皮の局所的な環境に大きな影響を与えます.
- ホルモン置換療法 (HRT) は,更年期症状と性機能障害に対してますます使用されています.
- HRTが髪の毛に与える影響を理解することは,その流行が増加しているため極めて重要です.
研究 の 目的:
- 髪の生物学における主要なホルモンであるエストロゲンとアンドロゲンの役割をレビューする.
- 様々なタイプのHRTとその臨床用途を概説する.
- 髪の成長と健康に対するHRTの影響に関する現在の証拠を要約します.
主な方法:
- 科学記事と臨床研究の文献レビュー.
- 毛皮に影響を及ぼすホルモン経路の分析.
- 様々なHRT製剤と,その報告された髪への影響に関するデータの統合.
主要な成果:
- エストロゲンとアンドロゲンは,髪の成長サイクルを調節する上で重要な役割を果たします.
- エストロゲンベースの,テストステロンベースの,および生物同一性ホルモン療法を含むHRTは,症状管理に使用されます.
- HRTが髪の毛に与える特定の影響に関する証拠は,リスクと利益について議論されているが,有限で複雑である.
結論:
- HRTが髪の毛に与える正確な影響は,まだ十分に理解されていません.
- ホルモン,毛囊,および地元の環境の複雑な相互作用は,HRTが髪に与える影響を複雑にします.
- HRTが髪の生物学と臨床結果に及ぼす影響を明らかにするために,さらなる研究が必要です.
さらに関連する動画
03:22Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia
Published on: January 27, 2018
15.7K
05:32Author Spotlight: Investigating the Relationship Between FSH and Pathophysiological Changes in Perimenopausal Women - Insights from a Mouse Model
Published on: August 11, 2023
2.6K
関連する概念動画
Menopause
5.0K
Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
5.0K
Accessory Structures of the Skin: Hair Growth and Types
2.6K
Hair growth begins with the production of keratinocytes by the basal cells of the hair bulb. As new cells are deposited at the hair bulb, the hair shaft is pushed through the follicle toward the surface. Keratinization is completed as the cells are pushed to the skin surface to form the shaft of hair that is externally visible. The external hair is completely dead and composed entirely of keratin. Hair can be cut or shaven without damaging the hair structure because the cut is superficial. Most...
2.6K
Hormonal Regulation of the Menstrual Cycle
1.8K
The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
1.8K
Bone Disorders
5.6K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
5.6K
Target Cell Response to Hormones
5.9K
Hormones intricately bind to receptors on the surface or within target cells, initiating a cascade of cellular responses.
Notably, the cellular response can be regulated by altering the number of receptors expressed in the cell. For example, prolonged exposure to elevated hormone levels results in a gradual decline or down-regulation in the number of receptors for that specific hormone on the cell surface. Conversely, in response to low hormone levels, cells may use up-regulation, producing an...
Notably, the cellular response can be regulated by altering the number of receptors expressed in the cell. For example, prolonged exposure to elevated hormone levels results in a gradual decline or down-regulation in the number of receptors for that specific hormone on the cell surface. Conversely, in response to low hormone levels, cells may use up-regulation, producing an...
5.9K
The Effect of Aging on Tissues
3.9K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
3.9K
